Elevations in superoxide dismutase and malondialdehyde [80], reductions in catalase or catalase gene polymorphism [81,82,83], increases in advanced oxidation protein products [84], nuclear factor erythroid 2-like 2 (Nrf2) gene polymorphism [85], and reduced Nrf2 activation [86,87] are associated with vitiligo susceptibility. Here, CAT is linked to vitiligo.