Moreover, NLRP6 deficiency leads to upregulation of p-p38 MAPK, p-ERK, and p-IκBα in some diseases, such as allogeneic hematopoietic stem cell transplantation (allo-HSCT) [34], peripheral nerve injury [35], and acute kidney injury (AKI) [36]. The gene discussed is NLRP6; the disease is peripheral nerve injury.