FGF2 overexpression leads to increased cell proliferation and invasion in cancer cells [34] and antibodies against either FGF2 or FGF receptors causes a 50% reduction in cell proliferation and cell invasion of PDAC cancer cells in rudimentary single cell type 2D cultures, respectively, suggesting FGF signalling could be a good therapeutic target [35,36]. Here, FGF2 is linked to cancer.