Likewise, independently of ethnicity, gender and age at diagnosis, PSRC1, but not SORT1 or CELSR2 mRNA levels, were independently associated with more advanced tumor stage (S >1; beta: 0.7 ± 0.06; 95% C.I. 0.05–0.27; p = 0.006), severe histological grade of liver cancer (G > 2; beta: 0.17 ± 0.06; 95% C.I. 0.05–0.29; p = 0.005) and primary tumor extension (T > 1; beta: 0.17 ± 0.05; c.i. 0.06–0.28; p = 0.003) (Figure S4A–C and Table 8). The gene discussed is CELSR2; the disease is neoplasm.