In vitro studies using various Gk plant derivatives (asiaticosides, asiatic acid, madecassoside, and madasiatic acid) showed that these compounds were capable of blocking H2O2-induced cell death, decreasing free radical concentration, and inhibiting β-amyloid cell death, suggesting a potential role for Gk in the treatment and prevention of Alzheimer’s disease [55,58,121,122]. This evidence concerns the gene GK and early-onset autosomal dominant Alzheimer disease.