Stucki et al. (2016) aimed to determine the cellular factors that provoke mitochondrial dysfunction in Spinocerebellar ataxia type 1 (SCA1) progression in Sca1154Q/2Q mice at a symptomatic stage while observing MitoQ’s restorative properties against SCA1 pathology [10]. This evidence concerns the gene CASP3 and spinocerebellar ataxia type 1.