On this basis, Peroxiredoxins (PRXs) constitute an important checkpoint for tumor development and growth [11], as they regulate the intracellular levels of various ROS (i.e., hydrogen peroxide) and influence the activation of pro-oncogenic signaling cascades, such as Extracellular signal-regulated kinases/mitogen-activated protein kinases (ERK/MAPK) and Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3) [12]. Here, STAT3 is linked to neoplasm.