Interestingly, a prospective study including angiographically confirmed stable CAD patients reported that among ten cytokines (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, TNF-α, granulocyte-macrophage colony stimulating factor and IFN-gamma) and hs-CRP, only elevated IL-8 serum levels were considered as a potential marker of long-term outcome [120]. This evidence concerns the gene TNF and coronary artery disorder.