KLRB1 and Epstein-Barr virus infection: However, the effects of EBV infection on the host’s genetic susceptibility (e.g., expression of BCL-2 (the Akt signaling pathway) [16], MYC (the TGF-β signaling pathway) [17], and p16INK4a (the cell cycle G1/S checkpoint signaling pathway) [7]) and immune response (e.g., expression of B2M [18], CD3 [19], and CD161 [20]) to LSCC have not been reported in detail.