TSPO and Alzheimer disease: Furthermore, inflammatory cells in the brain utilize glucose, and neuroinflammation has been demonstrated both in MCI and AD subjects when compared to controls with PET imaging by utilizing the radiotracers [11C]-(R)PK11195 [86] and [11C]-PBR28 [87,88] that bind to 18 kDa translocator protein (TSPO), a molecule that is overexpressed by activated microglial cells in the brain [86,87,88].