Resv also significantly suppresses the levels of IL-8 (interleukin 8) and iNOS (Inducible nitric oxide synthase) and improves the antioxidant status by upregulating the Nrf2/HO-1 (Nuclear factor-E2-related factor/Heme oxygenase-1) signaling pathway in the H. pylori-induced gastritis model [71]. The gene discussed is CXCL8; the disease is gastritis.