Among the clinicopathological factors, the low CLDN12 expression was significantly associated with the recurrence of cervical cancer (p = 0.0385), but not with younger age, histological type, FIGO stage, tumor size, vascular involvement, lymphatic involvement, lymph node metastasis, distant metastasis or chemoradiotherapy (Table 1). This evidence concerns the gene CLDN12 and cervical carcinoma.