CLDN12 and metastatic malignant neoplasm in the lymph nodes: Among the clinicopathological factors, the low CLDN12 expression was significantly associated with the recurrence of cervical cancer (p = 0.0385), but not with younger age, histological type, FIGO stage, tumor size, vascular involvement, lymphatic involvement, lymph node metastasis, distant metastasis or chemoradiotherapy (Table 1).