ANKRD11 and KBG syndrome: The current explorative study aims at defining both cognitive profile and adaptive behaviour, respectively assessed by Wechsler Intelligence Scales [21,22] and adaptive behaviour measures (Vineland Adaptive Behavior Scales-Second Edition-Survey Interview Form-VABS-II-SIF [23] or Adaptive Behavior Assessment System-Second Edition-ABAS-II [24]) in patients with a clinical diagnosis of KBG syndrome, confirmed by the identification of a ANKRD11 pathogenic mutation or with a 16q24.3 microdeletion.