CPB1 and cancer: We then compared the expression pattern of CPB1 in normal breast tissues (N = 475) vs. BC tissues (N = 5574) from GENT2 dataset and found a slight decrease in overall {mean: 7.8 (normal), 7.02 (cancer); median: 7.47 (normal), 6.13 (cancer)} expression of CPB1 in BC patients (p-value < 0.0001) (Figure 1B).