To confirm this, we stratified the BC dataset from a gene expression database (GENT2) consisting of 725 BC samples according to grade and observed a mean expression of CPB1 of 8.84, 7.54, and 5.55 in grade 1, 2, and 3, respectively (p-value < 0.0001; Figure 1D). The gene discussed is CPB1; the disease is breast cancer.