Within tumour vessels intravital imaging approaches to visualise the leucocyte-endothelium interactions, Turk and co-workers identified few crawling Ly6G+ neutrophils in the venules while CD8+ T cells crawled in both collecting and post-capillary venules, indicating different leucocyte subpopulations may crawl along distinct vascular structures or components within the TME (extracellular matrix, collagen, etc.)[75]. The gene discussed is CD8A; the disease is neoplasm.