In addition, studies have confirmed that after inhibiting the expression of TBX5, the up-regulation of exosomal miR-10b levels simultaneously causes the down-regulation of PTEN and another tumor suppressor, Dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A), which ultimately affects BC invasion and migration [39,40]. This evidence concerns the gene PTEN and breast cancer.