FOXO1 and pancreatic neoplasm: Baicalin could promote apoptosis in pancreatic cancer cells (SW1990 cell line) via dose-dependent upregulation of the expression of mitochondrial Bax (Bcl2-associated Xprotein) and cleavage-type enzymes caspase-3, and p53, consequently significantly decreasing B-cell lymphoma/lymphoma 2 (Bcl-2) protein levels, possibly activating c-Jun N-terminal kinase/forkhead box protein O1/Bcl-2 interacting mediator of cell death (JNK/Foxo1/BIM) pathway [39].