RGL2 and colorectal carcinoma: To ascertain the possible mechanism for RGL2-promoted CRC metastasis, we performed Spearman’s correlation test against RGL2 coexpression with other somatic genes detected by RNA-sequencing experiments in the TCGA CRC samples with higher RGL2 expression in Kaplan-Meier analysis and a record of lymph node metastasis (Figure 5A).