On the other hand, cytokine–cytokine receptor interaction, salmonella infection, inflammatory mediator regulation of TRP channels, adrenergic signaling in cardiomyocytes, amoebiasis, African trypanosomiasis, parathyroid hormone synthesis, secretion and action, NF-kappa B signaling pathway, inflammatory bowel disease, and Kaposi sarcoma-associated herpesvirus infection are identified as enriched and thereby potentially activated in EMM. This evidence concerns the gene IL18R1 and Herpesviridae infectious disease.