EGFR and neoplasm: Other studies described how glioblastoma-associated macrophages and microglia are the predominant factors in the tumor microenvironment by elucidating the role of MerTK in this context [121], clarifying the involvement of epidermal growth factor receptor (EGFR) and colony stimulating factor 1 receptor (CSF-1R) signaling [122], and the activity of microglia by AAV2-mediated IL-12 through TRAIL [123] as well as the role of TNF-α [124].