BID and cancer: In human prostate carcinoma LnCaP cells, TQ deceased cell viability and increased apoptosis by activating caspase-9 [100], and inhibited the growth of human prostate C4-2B cancer cells with the activation of JNK and growth arrest and DNA damage inducible gene (GADD45a), upregulating induce apoptosis factor-1 and decreasing Bc12-related proteins, such as BAG-1, Bcl2, Bcl2A1, Bcl2L1 and BID [101].