Furthermore, in human adenocarcinoma MDA-MB-231 triple negative cells, TQ inhibited the overexpression of chemokine receptor type 4 (CXCR4), by downregulating NF-kβ, decreased cell invasion and migration, reduced the expression of Bcl-2, Bcl-xL and survivin and activated the peroxisome proliferator-activated receptors (PPAR)-γ pathway [38,39]. This evidence concerns the gene BCL2 and adenocarcinoma.