To the best of our knowledge, two in vivo studies were performed on mice: the first highlighted the anticarcinogenic mechanism of TQ in tumor xenograft nude mice by blocking EMT through the downregulation of N-cadherin, β-catenin and vimentin proteins and suppressed lung metastasis [90], the latter showed the ability of TQ in inducing apoptosis through pro-oxidant effects in tumor xenograft nude mice [86]. The gene discussed is CDH2; the disease is neoplasm.