Therefore, oxyresveratrol might be a useful tool to treat autoimmune and chronic inflammatory diseases, such as inflammatory bowel diseases, psoriasis, ankylosing spondylitis, multiple sclerosis, asthma, Crohn’s disease, ulcerative colitis, Alzheimer’s diseases and rheumatoid arthritis, in which IL-12, TNF-α, and IL-6 have been found to play an important role [7,36,37,38,39]. The gene discussed is TNF; the disease is rheumatoid arthritis.