LRP1 and inherited lipid metabolism disorder: It is also possible that LRP-1 and sLRP-1 levels in OSA depend on the magnitude of dyslipidaemia as Calvo et al. detected a direct association between circulating sLRP-1 levels and total cholesterol and LDL-C in subjects with severe hypercholesterinaemia (LDL-C > 190 mg/dL) [38].