Contrary to our results, in a recently published article on VDR [40], two vitamin D bioactivating cytochrom P450 isoforms (CYP27A1, CYP2R1), gene polymorphisms, and lipid profile in RA showed that vitamin D deficiency was an independent predictor of higher DAS 28, HAQ scores, and affected joint counts exclusively in the VDR FokI Ff/ff genotype group in a multivariate regression analysis (p < 0.05). Here, CYP2R1 is linked to vitamin D deficiency.