For example, it was found that autoantibodies against p210, a native epitope of human ApoB100, are associated with a reduced severity of atherosclerosis in humans [18,19], and immunization of mice with antibodies directed against native p210 had an anti-atherogenic effect [20,21], raising the possibility of a similar role of the corresponding autoantibodies. This evidence concerns the gene EVPL and atherosclerosis.