NETs, which are extracellular DNA structures covered by neutrophil antimicrobial peptides (LL-37 and HNP-human neutrophil peptide), are abundantly released by neutrophils of SLE patients and represent the link between these cells and the IFN-α signaling in SLE and LN [43,44,46]. Here, IFNA1 is linked to systemic lupus erythematosus.