Proximal tumor-gained promoters (‘gained.TSS’ regions) significantly enriched with EZH2 (p-value < 1.6 × 10–16, Fisher’s exact test) and SUZ12 (p-value < 3.5 × 10–15, Fisher’s exact test) binding sites (Figure 4a; Table S14). This evidence concerns the gene EZH2 and neoplasm.