For example, we observed that the HOOK2 gene in case 19 was highly expressed in the tumor sample (19T), but not in its matched normal (19N) and stroma (19S) samples, while those genes around HOOK2 (SNORD41, TRIR, and JUNB) had similar levels of expression in all three samples (Figure 1b). The gene discussed is HOOK2; the disease is neoplasm.