NRG1 and pleural mesothelioma: We collected the methylation profile of pleural mesothelioma [69], and found 8 novel interactors to be hypomethylated in pleural mesothelioma versus non-tumor pleural tissue, namely, ACVR1B, IL6, MGMT, NRG1, OAT, PHLDA2, PLAUR and TNC (Table S3).