Amplification of the 3q26 region and overexpression of the SEC62 gene have been found in several cancer entities over the past decades including head and neck squamous cell carcinomas (HNSCC) [10,11], prostate cancer [12], esophageal cancer [13], cervical cancer [14,15], ovarian cancer [16], breast cancer [17], and non-small cell lung cancer (NSCLC) [18]. The gene discussed is SEC62; the disease is head and neck squamous cell carcinoma.