HDAC6 and central nervous system cancer: We found that inhibiting HDAC6 induces a rapid decrease of aaTub in the glioma cell cilia and an increase in the somas, which is a surprising observation since other groups have shown that HDAC6 localizes around the ciliary base and within the cilia [20,21], suggesting that inhibiting its deacetylase function would increase aaTub in the cilia.