IL15RA and Miyoshi myopathy: After a sublethal dose of doxorubicin or sublethal dose of melphalan was administered to MM cells, Borrelli et al. found that the drugs could not only cause MM cells to secrete more exosomes but also enhance the expression of the IL-15/IL-15RA complex on the surfaces of MM cells and exosomes via inducing senescence [62].