One study has shown that MM-derived exosomes are enriched in miRNA-146a, which can be transferred into MSCs, causing the increased secretion of cytokines and chemokines, including chemokine (C-X-C motif) ligand 1 protein (CXCL1), IL-6, IL-8, MCP-1 and CC chemokine ligand 5 (CCL-5). This evidence concerns the gene CXCL1 and Miyoshi myopathy.