This was accompanied by a significant decrease in production of pro-inflammatory cytokines and chemokines (comparison to non-treated granuloma controls), including those related to Th1 lymphocytes (IL-2R, IL-7, TNF-α, IFN-γ) and macrophages (CCL2 (MCP-1, CCL3 (MIP-α), CCL4 (MIP-1β), GM-CSF) and others typical of inflammation (IL-6, IL-8, IFN-α) [123]. The gene discussed is CCL2; the disease is Granuloma.