INSR and fetal growth restriction: At 2 days of age, our IUGR animals showed lower expression in the liver of Igf1 and Igf2, and in the muscle of Igf2. In contrast, at 10 days, IUGR animals featured higher liver expression of Insr and higher brain expression of Igf2r. We hypothesize that the high expression of receptors in the IUGR group may be a mechanism destined to offset the lower production of IGFs detected on Day 2 of life.