Deletion of ANLN caused nephrotic phenotype in zebrafish, and to date, two heterozygous mutations in the ANLN gene (c.1852G>T: p.G618C and c.1291C>T: p.R431C) have been reported in familial focal segmental glomerulosclerosis (FSGS) patients [66]. The gene discussed is ANLN; the disease is focal segmental glomerulosclerosis.