Zinc deficiency might be explained by insufficient intake (e.g., anorexia, low dietary content in food, poor bioavailability from foods, compromised intestinal absorption) or a defect in metabolism and zinc distribution caused by dysregulation of homeostasis mechanisms (e.g., defects in zinc transporters ZIP and ZnT, in binding proteins MT) [100]. The gene discussed is MCAT; the disease is Zinc deficiency.