This drug is not recommended to be used in the cases of lymphocytes < 200 cells/mmc, neutrophils < 500 cells/mmc, platelets < 50,000 cells/mmc, hemoglobin < 8 g/dL, AST/ALT values greater than 5 times of its normal upper limit, creatinine clearance ≤ 30 mL/min, sepsis, liver failure, and tuberculosis [21]. Here, GPT is linked to tuberculosis.