LRRK2 and Parkinson disease: Thus, we have analyzed the LRRK2 interactome in brain tissues majorly affected in PD; such as the substantia nigra, basal ganglia, frontal cortex, and anterior cingulate as well as the cerebellum as region unaffected by PD pathology (Braak et al., 2003, Dijkstra et al., 2014, Poewe et al., 2017).