RYR3 and Sinus bradycardia: Table 2 presents the list of top 19 prioritized genes related to sinus bradycardia with an overall P value less than 0.05. Two genes RYR3 and CTNNA3 showed the highest correlation priority to sinus bradycardia, due to average scores more than 0.8 and overall P values less than 1× 10−5. Average scores of other 17 genes ranged between 0.2 and 0.7 (Table 2).