IGHE and atopic eczema: Atopic dermatitis (eczema) is a common inflammatory skin disorder,1,2 with a global prevalence in children ranging from 7% to 25%, and is associated with significant morbidity and health care costs.2,3 Atopic dermatitis typically begins in early childhood and is characterized by fluctuating intensely pruritic skin lesions4 that may or may not persist into adulthood.2 Children who have atopic dermatitis with specific IgE antibodies are at an increased risk for development of allergic rhinitis, food allergies, and asthma.4