iPathwayGuide analysis performed showed that the top cancer-related signatures activated by TAZ-CAMTA1 in SW872 cells (Figure 3H) are the PI3K-Akt signaling pathway, Hippo signaling pathway (Figure 3—figure supplement 1B), focal adhesion, proteoglycans, and extracellular matrix (ECM)-receptor interaction (mirroring qRT-PCR results in Figure 3F and G). Here, AKT1 is linked to cancer.