Moreover, most of the previous studies focused on the role of a certain gene in PDAC, and most of them studied the effect of genes on the function of PDAC cells, for example: Yang et al. (2020) found that chlorogenic acid can inhibit cell bioenergy by regulating the c-Myc-TFR1 axis, thereby inhibiting pancreatic cancer. Here, MYC is linked to familial pancreatic carcinoma.