RUNX2 and Miyoshi myopathy: lncRNA RUNX2-AS1 is enriched in MSCs from MM patients, and it can be packaged into exosomes derived from myeloma cells and transferred to MSCs and then transcriptionally inhibit the expression of RUNX2 by reducing its splicing efficiency, thereby decreasing the osteogenic effects of MSCs (Li B. et al., 2018).