In addition, CAF-derived exosomal miR-196a can be uptaken by head and neck cancer (HNC) cells and enhances cell growth and cisplatin resistance, which may be mediated by the translocation of heterogeneous nuclear ribonucleoprotein A1 (hnRNPA1) and directly downregulate the expression of CDKN1B and ING5 (Qin et al., 2019). Here, HNRNPA1 is linked to head and neck cancer.