NLRP3 and acute kidney injury: Activation of NLRP3 inflammasome was also found in mouse models of cisplatin-induced AKI (Ullah et al., 2020; Yang et al., 2020), which was positively regulated by heat shock protein 70 (Ullah et al., 2020) or mtROS (Ma et al., 2019; Yang et al., 2020).