In addition, after PD injection, mice transplanted with c-Myc-overexpressed CaSki cells showed larger tumor volumes and weights and a faster growth rate than the mice injected with empty vector-overexpressed CaSki cells (Figures 7B–D), which suggested that PD can inhibit tumorigenesis in vivo and that the inhibition can be reversed by overexpression of c-Myc. The gene discussed is MYC; the disease is neoplasm.