We propose five main mechanisms that potentially explain the role of LINC00460 in the increased prognosis of BRCA patients: (1) regulation/co-expression of good prognosis-related genes, (2) co-expression/modulation of genes that promote an immunogenic niche, (3) decrease of tumor cell proliferation, (4) regulation of WNT7A through sponging of miR-103-a-1 and (5) promoting chemotherapy (anthracycline) complete pathologic response. The gene discussed is WNT7A; the disease is neoplasm.