LINC00460 over-expression is strongly associated with poor survival rates in different tumors, such as lung, ovary, larynx, nasopharynx, head and neck, meningioma, kidney, thyroid, colorectal, glioma, osteosarcoma, bladder and cervix (31, 35, 48–56). The gene discussed is LINC00460; the disease is central nervous system cancer.