Similarly, the mean percentage of HLA-B, -C heavy chain expression was significantly higher in dedifferentiated than in conventional chondrosarcoma: 90% ± 1.5 (mean expression of the 20 dedifferentiated chondrosarcoma analyzed, range 85-90%) versus 42% ± 26 (mean expression of the 52 conventional chondrosarcoma analyzed, range 10-85%), p<0.0001. The gene discussed is HLA-B; the disease is chondrosarcoma.