CD4 and disease arising from reactivation of latent virus: However, our previous studies of HCMV latent infection in CD34+ progenitors showed that the latent secretome was also able to suppress inflammatory cytokine production by CD4+ T cells due to the presence of immunomodulatory cytokines including cIL-10 and TGF-β (32) as well as HCMV vIL-10 (35).