NFE2L2 and tuberculosis: Hence, the present study investigated the effect of TB supplementation on growth performance, plasma antioxidant and immune capacity indexes, PI3K/Akt/Nrf2 signaling and inhibition of the NF-κB signaling pathway and performed pathological examinations to assess the role of TB in regulating health status and to elucidate the related mechanism in juvenile blunt snout bream.