In fact, complex models, such as Eμ-Myc/BCRHEL/sHEL to mimic Burkitt’s lymphoma, or IL-14α TG × c-Myc TG (DTG) mice for blastoid-variant mantle-cell lymphoma (MCL-BV) are good examples (73, 74). This evidence concerns the gene MYC and mantle cell lymphoma.