MYC and Immunodeficiency: However, multiple mouse models with other Myc translocations develop different B-cell malignancies, such as Vκ-Myc mice for myeloma (29), λ-Myc for Burkitt’s lymphoma (30), iMycEμ for endemic Burkitt’s lymphoma (31), and iMycCμ mice for sporadic and immunodeficiency-associated Burkitt’s lymphoma (32), demonstrating the critical role of c-Myc in B cell biology.