CXCL10 and infection: In the late phase of infection, a large increase in delayed type I IFN responses occurs, which induces the secretion of proinflammatory cytokines such as C-X-C motif chemokine ligand 10 (CXCL10) found in pulmonary autopsy tissues, and recruits and activates inflammatory monocyte-macrophages, resulting in the impairment of T cell responses and lung immunopathology (34, 35).